Regenerative therapy for hypoplastic left heart syndrome: First report of intraoperative intramyocardial injection of autologous umbilical-cord blood–derived cells
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چکیده
منابع مشابه
Hypoplastic left heart syndrome
Hypoplastic left heart syndrome (HLHS) refers to the abnormal development of the left-sided cardiac structures, resulting in obstruction to blood flow from the left ventricular outflow tract. In addition, the syndrome includes underdevelopment of the left ventricle, aorta, and aortic arch, as well as mitral atresia or stenosis. HLHS has been reported to occur in approximately 0.016 to 0.036% of...
متن کاملHypoplastic left-heart syndrome.
Hypoplastic left heart syndrome may be accurately diagnosed during fetal life. Prenatal diagnosis provides the opportunity for parents to make an informed choice about their options, including surgery, nonintervention postnatally or termination of pregnancy. Short to medium term survival continues to improve for a condition that was previously invariably lethal. There continues to be a signific...
متن کاملDefinitive therapy for hypoplastic left heart syndrome - Indian scenario.
When most of the centers in India do not entertain the patients with hypoplastic left heart syndrome, the original authors of the article in the present issue should be congratulated for the attempt of treating this patient with hybrid procedure. It’s a spectacular beginning. The development of staged reconstructive surgery for hypoplastic left heart syndrome (HLHS) by Norwood and colleagues in...
متن کاملPreoperative management of hypoplastic left heart syndrome.
Hypoplastic left heart syndrome (HLHS) is the most common functional single ventricle congenital cardiac defect. This syndrome is characterised by a functional single right ventricle and systemic outflow obstruction. The systemic and pulmonary circulations compete for cardiac output with a resultant precarious balance among systemic, pulmonary and coronary blood flows. A once fatal diagnosis, a...
متن کاملSingle film retrograde umbilical aortography in the diagnosis of hypoplastic left heart syndrome with aortic atresia.
Single film retrograde umbilical aortography was used successfully in confirming the diagnosis of hypoplastic left heart in three neonates. The method involves injecting Renografin 75% (1.25 cc/kg body weight) into the umbilical artery catheter according to the following sequence. First, the tip of the catheter is positioned at the level of the ductus arteriosus. The infant heart beats are then...
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ژورنال
عنوان ژورنال: The Journal of Thoracic and Cardiovascular Surgery
سال: 2015
ISSN: 0022-5223
DOI: 10.1016/j.jtcvs.2014.10.093